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Genital Worts and Human Papilloma Virus 

HPV is the most common tumor of the vulva. The incubation period varies from weeks to months.

Clinical evaluation of genital worts

Condyloma acuminata lesions appear as rough, verrucous papillomas on the genitalia. Enlargement often occurs during pregnancy.

No practical screening tests for subclinical infection exist. Pap smear diagnosis of HPV does not correlate well with detection of HPV DNA.

Treatment of genital worts and perianal warts

Cryosurgery with liquid nitrogen or cryoprobe is more effective.

Podophyllin 25% in of benzoin may be applied and washed off 4 hours later. Two or 3 applications, 1 week apart, may be needed. Podophyllin should not be used on the vagina or cervix; it is contraindicated in 25% in of benzoin may be applied and washed off 4 hours later. Two or 3 applications, 1 week apart, may be needed. Podophyllin should not be used on the vagina or cervix.

Podofilox 0.5% ( Condylox) solution for self-treatment: Apply twice daily for 3 days followed by 4 days of no therapy.

Surgical excision and electrocoagulation or laser.

Large, bulky or extensive lesions

General anesthesia and wire loop cautery is effective.

Topical 5-fluorouracil cream in a 1-2% concentration is effective in the treatment of vaginal condylomata.

Recurrence rates are high (25% within 3 months).

Partner referral for genital worts

Annual Pap smears are recommended for partners.

The use of condoms may reduce spread.

 Solution for self-treatment: Apply twice daily for 3 days followed by 4 days of no therapy.

Surgical excision and electrocoagulation or laser

Large, bulky or extensive lesions

General anesthesia and wire loop cautery is effective.

Topical 5-fluorouracil cream in a 1-2% concentration is effective in the treatment of vaginal condylomata.

Recurrence rates are high (25% within 3 months).

 

 

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